Autologous means that the donor and the recipient are the same person. The eye drops in this case are made from your own blood. Red blood cells and clotting factors are removed, leaving behind blood serum. This is diluted with a sterile, preservative-free solution to produce a tear substitute that is unique to the patient, and contains many important growth factors and nutrients normally found in healthy tears. Since blood and tears have an almost identical salinity and pH, there is no issue of burning or stinging upon instillation. Because they are non-preserved, the drops are stored in the freezer until you need them.
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